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Michael Hedvat Selected Research

Proto-Oncogene Proteins c-akt (Protein Kinase B)

1/2010Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways.
11/2008Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas.

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Michael Hedvat Research Topics

Disease

12Neoplasms (Cancer)
11/2012 - 06/2004
3Medulloblastoma
04/2012 - 11/2008
2Melanoma (Melanoma, Malignant)
05/2012 - 05/2011
2Carcinogenesis
11/2011 - 12/2009
2Prostatic Neoplasms (Prostate Cancer)
05/2011 - 06/2004
1Colorectal Neoplasms (Colorectal Cancer)
05/2012
1Neoplasm Metastasis (Metastasis)
11/2011
1Neurodegenerative Diseases (Neurodegenerative Disease)
10/2011
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
10/2011
1Alzheimer Disease (Alzheimer's Disease)
10/2011
1Huntington Disease (Huntington's Disease)
10/2011
1Glioma (Gliomas)
04/2010
1Glioblastoma (Glioblastoma Multiforme)
04/2010

Drug/Important Bio-Agent (IBA)

31,1',6,6',7,7'- hexahydroxy- 3,3'- dimethyl- N5- (2- phenylpropyl)- N5'- (2- phenylpropyl)- 2,2'- binaphthyl- 5,5'- dicarboxamideIBA
11/2012 - 05/2011
3Phosphotransferases (Kinase)IBA
11/2011 - 06/2004
2Pharmaceutical PreparationsIBA
11/2012 - 06/2004
2apogossypolIBA
05/2012 - 05/2011
2InterleukinsIBA
05/2012 - 05/2011
2Apoptosis Regulatory ProteinsIBA
04/2012 - 11/2008
2Small Interfering RNA (siRNA)IBA
04/2012 - 12/2009
2AZD 1480IBA
11/2011 - 12/2009
2CytokinesIBA
05/2011 - 12/2009
2Sorafenib (BAY 43-9006)FDA Link
04/2010 - 11/2008
2Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2010 - 11/2008
2STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2010 - 11/2008
1GossypolIBA
11/2012
1AD 5IBA
05/2012
1Bortezomib (Velcade)FDA Link
04/2012
1benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketoneIBA
04/2012
1CaspasesIBA
04/2012
1Proteasome InhibitorsIBA
04/2012
1Janus KinasesIBA
11/2011
1Proteins (Proteins, Gene)FDA Link
10/2011
1Glutamic Acid (Glutamate)FDA Link
10/2011
1ABT-737IBA
05/2011
1Interleukin-10 (Interleukin 10)IBA
05/2011
1Transcription Factors (Transcription Factor)IBA
05/2011
1Tyrosine Kinase InhibitorsIBA
01/2010
1Sunitinib (Sutent)FDA Link
01/2010
1Angiogenesis InhibitorsIBA
01/2010
1Cytokine Receptors (Cytokine Receptor)IBA
12/2009
1Mitogen-Activated Protein Kinase 3IBA
11/2008
1Mitogen-Activated Protein KinasesIBA
11/2008
1PPAR gammaIBA
06/2004
1AndrogensIBA
06/2004
1Etodolac (Lodine)FDA LinkGeneric
06/2004
1Cyclin D1IBA
06/2004

Therapy/Procedure

4Therapeutics
11/2012 - 01/2010